Adult & childn ≥12 yr 1 tab once daily. Severe hepatic impairment Adult & childn weighing >30 kg Initially 10 mg every other day, childn weighing ≤30 kg 5 mg every other day.
Discontinue treatment if arrhythmia occurs. May cause drowsiness. Avoid ethanol or composition w/ alcohol; QT prolonging medications eg, Ca channel blockers (eg, bepridil, verapamil), TCA, cisapride, quinidine. Concomitant use w/ macrolides (eg, erythromycin, clarithromycin); imidazole antifungals (eg, ketoconazole, itraconazole, fluconazole); HIV PIs; CYP450 inhibitors eg, cimetidine, metronidazole, zafirlukast, SSRIs. May be at risk of falling from the height in patient who drive or operate machines. Severe hepatic impairment. Pregnancy (1st trimester). Not recommended during lactation. Childn <2 yr.
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