Patients with severe liver impairment should be administered a lower initial dose because they may have reduced clearance of Loratadine. An initial dose of 10 mg every other day is recommended for adults and children weighing more than 30 kg, and for children weighing 30 kg or less, 5 mg is recommended.
Effects on ability to drive or use machines: Loratadine had no or negligible influence on the ability to drive and use machines.