Dissolution of radiolucent, non-calcified gallstones in patients who are not candidates for cholecystectomy. Primary biliary cirrhosis. Prevention of gallstone in obese patients undergoing rapid wt loss.
View Ursolin overdosage for action to be taken in the event of an overdose.
Administration
Should be taken with food.
Contraindications
Hypersensitivity or intolerance. Allergy to bile acids. Calcified cholesterol, radiopaque or radiolucent bile pigment stones. Patients w/ reasons for cholecystectomy eg, unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis or biliary GI fistula.
Patients w/ congenital or acquired deficiency in sulfation predisposing to lithocholate-induced liver damage. Patients w/ variceal bleeding, hepatic encephalopathy, ascites, or in need of urgent liver transplant. Measure AST & ALT at initiation of therapy & thereafter. Not recommended during pregnancy. Lactation. Childn. Elderly.
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