Chemotherapy-induced thrombocytopenia in patients w/ solid tumour. Patients w/ platelet count <50 x 109/L & are considered necessary to have increased platelet count.
300 U/kg SC once daily for 14 continuous days. Patients w/ malignant solid tumor receiving chemotherapy where dosage is predicted to induce thrombocytopenia & hemorrhage300 U/kg SC once daily every 6-24 hr after chemotherapy for 14 continuous days. Discontinue therapy when platelet count recovers to ≥100 x 109/L during administration or if the absolute increment of platelet count is ≥50 x 109/L.
Hypersensitivity. Patients w/ severe cardio-cerebral vascular angiopathy, w/ blood agglutination or recent history of thrombosis. Severe infection must be controlled before using TPIAO.
May excessively increase platelet count in patients w/ idiosyncrasy. Perform periodic routine blood test once every other day; before therapy & in 2 wk at least after w/drawal. Routine blood tests eg, platelet count & peripheral blood smear must be monitored before, during & after therapy. Pregnancy & lactation.
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