IM 0.5 mL dose in deltoid for adult & anterio-lateral region of thigh for childn. Intradermal 0.1 mL dose (per site) in upper arm. Pre-exposure schedule 2 inj on Days 0 & 7. Persons at high risk of contacting rabies virus or immunodeficiency 3 inj on Days 0, 7 & 21 or 28. Post-exposure schedule Non-immunized subjects IM 5 inj (0.5 mL) on Days 0, 3, 7, 14 & 28. Intradermal 1 dose (0.1 mL) at 2 different sites, left & right upper arm on Days 0, 3, 7 & 28. Fully immunized subjects Vaccine exposure <6 mth: 1 inj on Day 0; >6 mth: 2 inj on Days 0 & 3.
Pre-exposure prophylaxis immunization: Hypersensitivity. Avoid use in person w/ seriously chronic & hypersensitive disease; nervous system disease. Delay vaccination in active period of acute fever & pregnancy.
Do not inj IV. Not to be administered vaccine & anti-rabies Ig in same inj site. Administer immediately a new dose intradermally if vaccine is inadvertently given SC or IM. Not to be administered intradermally in individuals receiving long-term corticosteroid or other immunosuppressive therapy or chloroquine. Immunocompromised individuals.
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