Speeda Dosage/Direction for Use

To reconstitute the vaccine, introduce the diluent 0.5 ml into the vial of powder and wait until the powder is dissolved completely. The solution should be homogenous, clear and free of any particles. Withdraw the solution in a syringe.
Intramuscular administration: The 0.5 ml dose of vaccine shall be injected intramuscularly in the deltoid in adults and in the anterio-lateral region of the thigh in young children. Do not inject in the gluteal region.
Intradermal administration: The 0.1 ml dose of vaccine (per site) shall be injected intradermally in upper arm.
Pre-exposure schedule: 2 injections on Day 0, Day 7.
The persons at high risk of contacting rabies virus or immunodeficiency shall be vaccinated 3 injections on day 0, day 7 and day 21 or 28.
Post-exposure schedule: Auxillary therapy: The treatment of wound is very important and must be performed promptly after the bite. It is recommended firstly to wash the wound with large quantity of water and soap and with detergent and then apply 70% alcohol, tincture of Iodine or 0.1% Quaternary Ammonium Solution (provided no soap remains as the two products neutralize each other). Curative vaccination must be administered under medical supervision and only in rabies treatment centre.
Vaccination of non-immunized subjects: Intramuscular schedule (Standard intramuscular regimen: ESSEN): Five injections (0.5 ml) will be given intramuscularly on day 0, 3, 7, 14 and 28.
Intradermal schedule (Modified TRC-ID regimen, 2-2-2-0-2): One dose of vaccine, in a volume of 0.1 ml is given intradermally at two different sites, usually the left and right upper arm on days 0, 3, 7 and 28.
In the case of type III, anti-rabies immunoglobulin should be administered as well on day 0. The rabies vaccine should be administered in different injection site.
Vaccination of subjects already fully immunized against Rabies: If vaccine administered in less than 6 months of exposure (cell culture rabies vaccine): Then 1 injection on D0 is recommended.
If vaccine administered in more than 6 months of exposure (cell culture rabies vaccine): Then 2 injections on D0, D3 are recommended.