Recommended Dosage: Dosing Guidelines: HYDEX dosing should be individualized and titrated to desired clinical response.
HYDEX is not indicated for infusions lasting longer than 24 hours.
HYDEX should be administered using a controlled infusion device. (See Table 1.)
Click on icon to see table/diagram/image
Preparation of Solution: Strict aseptic technique must always be maintained during handling of HYDEX. Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.
HYDEX must be diluted with 0.9% sodium chloride solution to achieve required concentration (4 mcg/mL) prior to administration. Preparation of solutions is the same, whether for the loading dose or maintenance infusion. To prepare the infusion, withdraw 2 mL of HYDEX Injection Concentrate, and add to 48 mL of 0.9% sodium chloride injection to a total of 50 mL. Shake gently to mix well.
Route of Administration: Intravenous infusion.