Heberbiovac-HB Dosage/Direction for Use

Intramuscular injection.
DOSAGE: Adults and children of 10 years and older: A dose of 20 μg.
Neonates, and children under 10 years: A dose of 10 μg.
There are two different schedules: 2 doses at 1 month interval, followed by a third dose 6 months after the first (0-1-6).
3 doses all month interval, followed by a reactivation booster dose a year later (0-1-2+12). This schedule is recommended in cases where there is an immediate risk of infection.
The preparation should be administered by deep intramuscular injection in the deltoid region, or in the anterolateral region of the thigh in neonates. Other forms of administration are not recommended.
In immunodepressed patients, protective levels of antibodies may not be attained and higher doses (usually twice the normal dose) could be necessary.
Patients with renal insufficiency including patients undergoing haemodialysis 16 years of age and above: The primary immunisation schedule for patients with renal insufficiency including patients undergoing haemodialysis is four doses of 40 μg (2 ml) at 0, 1, 2 and 6 months from the date of the first dose. The immunisation schedule should be adapted in order to ensure that the anti-HBs antibody titre remains equal to or higher than the accepted protective level of 10 IU/L.
SHAKE WELL BEFORE USE.