Dysmenorrhoea 10 mg bid from day 5-25 of cycle.
Endometriosis 10 mg bid to tid from day 5-25 of cycle or continuously.
Dysfunctional bleeding To arrest bleeding: 20 or 30 mg daily to be given up for 10 days. To regulate bleeding: 10 or 20 mg daily during 2nd half of the menstrual cycle.
Secondary amenorrhoea 10 or 20 mg daily to be given for 14 days during the 2nd half of the menstrual cycle.
Premenstrual syndrome 10 mg bid starting w/ the 2nd half of the menstrual cycle until the 1st day of the next cycle.
Irregular cycles 10 or 20 mg daily starting w/ the 2nd half of the menstrual cycle until the 1st day of the next cycle.
Threatened miscarriage Initially up to 40 mg, then 10 mg 8 hrly until symptoms remit.
Recurrent miscarriage 10 mg bid until the 12th wk of pregnancy.
Infertility due to luteal insufficiency 10 or 20 mg daily starting w/ the 2nd half of the menstrual cycle until the first day of the next cycle. Treatment should be maintained for at least 3 consecutive cycles.
Luteal support as part of ART treatment 10 mg tid starting at the day of oocyte retrieval & continuing for 10 wk if pregnancy is confirmed.
HRT Continuous sequential therapy: Estrogen + 10 mg dydrogesterone added for the last 14 days of every 28 day cycle, in a sequential manner. Cyclic therapy: When estrogen is dosed cyclically w/ a treatment-free interval, usually 21 days on & 7 days off. 10 mg dydrogesterone is added for the last 12-14 days of estrogen therapy. Dose can be adjusted to 20 mg/day.
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