Cipol-N Description

Each 25 mg capsule contains cyclosporine (USP) (INN: Ciclosporin) 25 mg.
Each 100 mg capsule contains cyclosporine (USP) (INN: Ciclosporin) 100 mg.
Cyclosporine is a potent immunosuppressive agent which prevents graft rejection following allogenic transplantations, which improves success rates of transplantations and survival rates of patients.
This drug is a state-of-the-art microemulsion formulation of cyclosporine. The original formulation has interpatient and intrapatient variability in cyclosporine absorption owing to bile dependent absorption.
This drug is developed to overcome the variability associated with the original formulation by virtually bile-independent absorption. Therefore, the improved oral bioavailability and dose linearity see n with this drug can facilitate patient management: the new formulation allows more accurate dose titration in the clinical setting and reduces the risk of over exposure or under exposure to the drug and maintain optimal immunosuppression of patients.