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It is recommended to monitor patients receiving INTERFERON for long periods and in high doses with the following laboratory analyses: White blood cell and platelet count, dosage of hepatic enzymes (TGO and TGP), evaluation of renal function (urea, creatinine).
Patients with history of cardiac abnormalities should be monitored by ECG during INTERFERON administration since arrhythmia may occur in some cases.
Since INTERFERON may affect the functions of the Central Nervous System, patients should be prevented to be cautious to drive vehicles and operate equipment till good tolerance to treatment is assessed.
During INTERFERON administration, an adequate hydration should be maintained since the feasibility of hypertension occurrence is related to depletion of liquids.
