AmBisome Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Side Effects Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing

Concise Prescribing Info

Contents

Liposomal amphotericin B

Indications/Uses

Systemic mycotic infections eg, cryptococcosis, aspergillosis, disseminated candidiasis, mucormycosis, primary therapy of visceral leishmaniasis. Empirical treatment of febrile neutropenia.

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Dosage/Direction for Use

Visceral leishmaniasis 1-1.5 mg/kg/day for 21 days or alternatively 3 mg/kg/day for 10 days. Immunocompromised patients 1-1.5 mg/kg/day for 21 days.

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Overdosage

View AmBisome overdosage for action to be taken in the event of an overdose.

Contraindications

Hypersensitivity.

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Special Precautions

Renal function should be closely monitored. Patients receiving concomitant therapy w/ nephrotoxic drugs.

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Use In Pregnancy & Lactation

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Adverse Reactions

Fever, chills/rigors, hypokalaemia, nausea, vomiting, increased creatine, alkaline phosphatase & BUN, hypomagnesaemia, hypocalcaemia, hyperglycaemia, hyponatraemia, bilirubinaemia, abnormal LFTs, diarrhoea, abdominal pain, dyspnoea, flushing/vasodilitation, headache, back & chest pain, tachycardia, hypotension, rash, convulsion, bronchospasm, thrombocytopenia, anaphylactoid reaction, anaemia, phlebitis.

Drug Interactions

Antineoplastics, nephrotoxic drugs. Corticosteroids & corticotropin. Digitalis glycosides.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view AmBisome detailed prescribing information

Storage

View AmBisome storage conditions for details to ensure optimal shelf-life.

Description

View AmBisome description for details of the chemical structure and excipients (inactive components).

Action

View AmBisome mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antifungals

ATC Classification

J02AA01 - amphotericin B ; Belongs to the class of antibiotics. Used in the systemic treatment of mycotic infections.

Thai FDA Category

Presentation/Packing

Form

AmBisome infusion 50 mg

Packing/Price

(w/ filter) 1's

AmBisome

amphotericin b

Manufacturer:

Gilead

Distributor:

DCH Auriga