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General: When administered in the presence of high environmental temperature, can cause heat prostration (due to decreased sweating).
Effects on the Ability to Drive or Operate Machinery: Obutin may produce drowsiness. The patient should be cautioned regarding activities requiring mental alertness eg, operating a motor vehicle or other machinery or performing hazardous work while taking Obutin.
Use in pregnancy: The safety of Obutin administered to women who are or who may become pregnant has not been established. Therefore, Obutin should not be given to pregnant women unless in the judgement of the physician, the probable clinical benefits outweigh the possible hazards.
