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Enteral absorption of concomitantly administered medicines such as minerals (e.g. lithium), vitamins (B12), cardiac glycosides, coumarin derivatives, and carbamazepine may be delayed. For this reason, Mucilin should not be taken ½ to 1 hour before or after intake of other medicinal products.
If the product is taken together with meals in the case of insulin dependent diabetics it may be necessary to reduce the insulin dose.
Ispaghula husk should be used concomitantly with thyroid hormones only under medical supervision because the dose of the thyroid hormones may have to be adjusted. In order to decrease the risk of gastrointestinal obstruction (ileus) Ispaghula husk should only be used under medical supervision together with medicinal products known to inhibit the peristaltic movement (e.g. morphinomimetics, loperamide).
