Medsamic Special Precautions

Patients with irregular menstrual bleeding should not use Medsamic until the cause of the irregularity has been established. If menstrual bleeding is not adequately reduced by Medsamic, an alternative treatment should be considered.
Patients with a high risk for thrombosis (a previous thromboembolic event and a family history of thromboembolic disease) should use Medsamic only if there is a strong medical indication and under strict medical supervision.
Patients with disseminated intravascular coagulation (DIC), who require treatment with Medsamic, must be under the strict supervision of a physician experienced in treating this disorder.
The blood levels are increased in patients with renal insufficiency. Therefore a dose reduction is recommended, see Dosage & Administration.
In haematuria from the upper urinary tract blood clots can, in a few cases, lead to ureteric obstruction.
Clinical experience with tranexamic acid in menorrhagic children under 15 years of age is not available.
Convulsions have been reported in association with tranexamic acid treatment.
Effects on ability to drive and use machines: Tranexamic acid may cause dizziness and therefore may influence the ability to drive or use machines.