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Haemorrhage or risk of haemorrhage in increased fibrinolysis or fibrinogenolysis. Local fibrinolysis may occur in the following conditions: menorrhagia, prostatectomy and bladder surgery, haematuria, gastro-intestinal haemorrhage, epistaxis, ulcerative colitis, conisation of the cervix, and dental extraction in patients with coagulopathies. General fibrinolysis may occur in the following conditions and situations: Prostatic and pancreatic cancer, after thoracic and other major surgery, in obstetrical complications such as ablatio placentae and post partum haemorrhage, leukemia, liver diseases, in connection with thrombolytic therapy with streptokinase.
Hereditary angioneurotic oedema.
