Lobesol Special Precautions

Clobetasol propionate is one of the most potent topical corticosteroid preparations. It can suppress the hypothalamic-pituitary-adrenal axis following topical application, and HPA axis suppression has occurred following topical dosages as low as 2gm of the 0.05% cream daily. Because of the drug's potency and potential for causing adverse systemic effect during topical therapy, the usual dosage should not be exceeded and occlusive dressings should not be applied to areas of Clobetasol propionate application.
Visual disturbance: Visual disturbance may be reported with systemic and topical corticosteroid use. If a patient presents with symptoms such as blurred vision or other visual disturbances, the patient should be considered for referral to an ophthalmologist for evaluation of possible causes which may include cataract, glaucoma or rare diseases such as central serous chorioretinopathy (CSCR) which have been reported after use of systemic and topical corticosteroids.