Lobesol Overdosage

Symptoms and Treatment of Overdosage and Antidotes: Topically applied corticosteroids can be absorbed in sufficient amount to produce systemic effect. Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area or under an occlusive dressings should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid.
Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.
In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favourable response does not occur promptly, the corticosteroids should be discontinued until the infection has been adequately controlled.