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IXIFI is contraindicated in patients with a previous severe hypersensitivity reaction to infliximab products or any of the inactive ingredients of IXIFI (see Description) or any murine proteins [severe hypersensitivity reactions have included anaphylaxis, hypotension, and serum sickness] (see Precautions and Adverse Reactions).
IXIFI is contraindicated in patients with moderate or severe heart failure (New York Heart Association [NYHA] Functional Class III/IV) (see Precautions and Adverse Reactions).
IXIFI is contraindicated in patients with tuberculosis or other severe infections such as sepsis, abscesses, and opportunistic infections (see Precautions).
