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Pregnancy: Treatment with terlipressin during pregnancy is contraindicated (see Contraindications and Pharmacology: Toxicology: Preclinical safety data under Actions).
Terlipressin has been shown to cause uterine contractions and increased intrauterine pressure in early pregnancy and may decrease uterine blood flow. Terlipressin may have harmful effects on pregnancy and foetus.
Spontaneous abortion and malformation has been shown in rabbits after treatment with Terlipressin.
Breastfeeding: It is not known whether terlipressin is excreted in human breast milk. The excretion of terlipressin in milk has not been studied in animals. A risk to the suckling child cannot be excluded. A decision on whether to continue/discontinue breast-feeding or to continue/discontinue therapy with terlipressin should be made taking into account the benefit of breast-feeding to the child and the benefit of terlipressin therapy to the woman.
