Monitor BP, heart rate & fluid balance during treatment. Should be given IV to avoid local necrosis at the inj site. Patients w/ HTN or recognized heart disease; controlled Na diet; uncontrolled HTN, cerebral or peripheral vascular diseases, cardiac arrhythmias, CAD or previous MI; severe asthma or COPD. Not to be used in patients w/ septic shock w/ a low cardiac output; unstable angina or recent acute MI. Extreme caution in patients w/ a history of QT interval prolongation, electrolytic abnormalities, concomitant QT-prolonging medications; peripheral venous HTN or morbid obesity. Monitor serum creatinine at least daily in patients w/ renal insufficiency. Carefully monitor fluid balance & electrolytes. May affect ability to drive & use machines. Lactation. Childn. Elderly.