Duphalac oral solution contains a laxative called lactulose. Duphalac may contain small amounts of milk sugars (e.g. lactose), galactose, epilactose or fructose.
As a prebiotic substance, lactulose intensifies the growth of Bifidobacterium and Lactobacillus, while Clostridium and Escherichia coli may be suppressed, leading to alleviation of constipation.
Duphalac IS USED FOR: Constipation (infrequent bowel movements, hard and dry stools). To produce soft stools. For example, if the patient has haemorrhoids (piles) or after colon/anal surgery. Portal systemic encephalopathy (PSE), a liver disease causing confusion, tremor, decreased level of consciousness.
Take Duphalac diluted or undiluted. Swallow the medicine quickly. Do not keep it in the mouth. Take the dosage preferably once a day at the same time. During treatment with laxatives, drink sufficient amounts of fluids (6-8 glasses).
Dosing in constipation or for stool softening: Starting dose [Maintenance dose]: Adults 10 - 45 ml [10 - 25 ml]; Children (7-14 years) 15 ml [10 -15 ml]; Children (1-6 years) 5 - 10 ml [5 - 10 ml]; Infants under 1 year Up to 5 ml [Up to 5 ml].
Based upon treatment response the doctor may adjust the starting dose to the maintenance dose after a few days. Several (2-3) days of treatment may be needed before treatment effect occurs.
Dosing in Portal systemic encephalopathy (PSE) (for adults only): Starting dose: 30 - 50 ml THREE times daily.
This dose may be adjusted by the doctor to the maintenance dose to achieve 2 to 3 soft stools per day.
DO NOT TAKE DUPHALAC: If the patient is allergic to lactulose or any of the ingredients of Duphalac, suffer from galactosaemia, gastrointestinal obstruction, digestive perforation, or risk of digestive perforation.
CARE WHEN TAKING Duphalac: Consult a doctor, if: the desired results are not observed after several days of treatment, the patient experiences painful abdominal symptoms of unknown cause, or the side effects get serious.
Talk to a doctor/pharmacist before starting Duphalac if the patient suffers from any medical conditions, in particular, hereditary problems of galactose or fructose intolerance, Lapp lactase deficiency, glucose-galactose malabsorption. Dose may be taken in consideration in diabetics when using high doses for PSE. Long-term use of unadjusted doses/misuse can lead to diarrhoea and disturbance of electrolyte balance.
If the patient had taken too high a dose, the patient may experience diarrhoea and/or abdominal pain. Stop treatment until symptoms have subsided.
The patient may experience diarrhoea, flatulence, abdominal pain, nausea, vomiting and electrolyte imbalance due to diarrhoea.
Hypersensitivity, rash, pruritus, urticaria and erythema may occur.
STORE between 10°C and 25°C. Protect from light.
A06AD11 - lactulose ; Belongs to the class of osmotically acting laxatives.
Duphalac oral soln 67%
1000 mL x 1's;200 mL x 1's
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