Overdosage may produce drowsiness and disorientation or extrapyramidal reactions especially in children. Anticholinergic agents, antiparkinsonian agents or anticholinergic antihistamines can be used to control extrapyramidal reactions. There is no specific antidote to domperidone but in the case of overdosage, gastric lavage may be useful. These symptoms may disappear within 24 hrs.
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