Duobloc Dosage/Direction for Use

The physician will determine the amount of the daily dose and the length of time for which it must be taken. Do not interrupt or stop taking Duobloc without first checking with the doctor.
Essential Hypertension: Treatment should begin with 12.5 mg daily for the first 2 days. After that treatment can continue with 25 mg once daily. If the effect is insufficient, the dose may be increased to 25 mg twice daily for 14 days at the earliest. A single dose of 25 mg or total daily dose of 50 mg should not be exceeded.
Chronic Stable Angina: The recommended dose for initiation of therapy is 12.5 mg twice a day for the first 2 days. Thereafter, the recommended dosage is 25 mg twice daily. If necessary, the dosage may subsequently be increased at the intervals at least 2 weeks up to the recommended maximum daily dose of 100 mg given in divided doses (twice daily).