No case of toxic overdose has been observed to date in association with oral pharmaceutical forms of acetylcysteine. Volunteers were treated with a dose of 11.6 g acetylcysteine/day over 3 months without observing any severe side effects. Oral doses up to 500 mg acetylcysteine/kg BW were tolerated without any symptoms of intoxication.
Symptoms of intoxication: Overdoses may lead to gastrointestinal symptoms, such as nausea, vomiting and diarrhoea. Infants are at risk of hypersecretion.
Therapy of intoxication: If necessary, according to the symptoms.