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Cinnarizine may enhance the sedative effect of CNS depressants including alcohol, barbiturates, hypnotics, narcotic analgesics, tricyclic antidepressants, sedatives and tranquilisers.
The side effects of anticholinergic substances eg, atropine and tricyclic antidepressants may be enhanced by the concomitant administration of antihistamines.
Monoamine oxidase inhibitors may enhance the antimuscarinic effects of antihistamines.
