Active Gastric Duodenal Ulcer: 20 mg/day for 2-4 weeks.
Severe Duodenal Ulcer: 40 mg/day for 4-8 weeks.
Reflux Oesophagitis: 20 mg/day for 4-8 weeks.
Severe Erosive Oesophagitis: 20-40 mg/day for 4-8 weeks.
Zollinger-Ellison Syndrome: 60 mg/day, duration adjusted to response.
Dosage adjustment is not necessary in the elderly or in patients with renal or hepatic impairment.