Elores Description

ELORES is a novel antibiotic adjuvant entity (AAE) to combat antimicrobial resistance caused by multidrug resistance ESBL/MBL producing strains comprising of a third generation cephalosporin Ceftriaxone Sodium a beta lactam antibiotic, Sulbactam Sodium an irreversible β-lactamase inhibitor along with non antibiotic adjuvant Disodium Edetate for intravenous administration.
Ceftriaxone sodium is a third generation broad-spectrum cephalosporin with molecular formula C₁₈H₁₆N₈Na₂O₇S₃·3.5H₂O. It has a calculated molecular weight of 661.59 and contains 83 mg sodium per gram.
Sulbactam sodium is a derivative of basic penicillin nucleus. It is an irreversible β-lactamase inhibitor. Chemically it is Sodium penicillinate sulfone, chemical formula is C₈H₁₀NNaO₅S with a molecular weight of 255.22. It contains 92 mg sodium per gram.
Disodium Edetate is Sodium salt of Ethylene Diamine Tetra Acetate is a non antibiotic adjuvant entity. The chemical formula is C₁₀H₁₄N₂Na₂O₈·2H₂O and the molecular weight 372.24. It contains 114 microgram Sodium per milligram. Edetate is a cell membrane permeability enhancer, chelating agent, antioxidant and acts as a catalyst.
ELORES available in 1.5 g strength as a white to off-white sterile, dry powder consisting of Ceftriaxone Sodium/Disodium Edetate/Sulbactam Sodium packaged in tubular glass vials. The product does not contain any preservative and is for single use only. It is administered as intravenous injection. Each single dose 1.5 g vial of ELORES contains Ceftriaxone Sodium Ph. Eur. equivalent to Ceftriaxone 1000 mg, Sulbactam Sodium Ph. Eur. equivalent to Sulbactam 500 mg, Disodium Edetate Ph. Eur. 37 mg.