Derzid-N Use In Pregnancy & Lactation

Use in pregnancy: Betamethasone: Topical corticosteroids, especially the more potent ones, should not be used extensively in large amounts or for protracted periods in pregnant patient or in patients who are planning to become pregnant. Adequate and well-controlled studies in humans have not been done.
Studies in animals have shown that topical corticosteroids are systemically absorbed and may cause fetal abnormalities, especially when used in large amounts, with occlusive dressings, for prolonged periods of time, or if the more potent agents are used.
A dose-related increase in fetal resorptions was observed in rabbits and mice given betamethasone dipropionate intramuscularly. This effect was not observed in rats. Teratogenic effects (umbilical hernia, cephalocele, cleft palate) were observed in rabbits when betamethasone dipropionate was administered intramuscularly.
Neomycin: Problems in humans have not been documented.
Use in lactation: Betamethasone: It is not known whether topical corticosteroids are distributed into breast milk. However, problems in humans have not been documented. Topical corticosteroids should not be applied to the breasts prior to nursing.
Neomycin: It is not known whether topical neomycin is distributed into breast milk. However, problems in humans have not been documented.