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Risk-benefit should be considered when the following medical problems exist: Neomycin: Sensitivity to aminoglycosides.
Betamethasone: Allergy to corticosteroids. Infection at treatment site (may be exacerbated if no appropriate antimicrobial agent is used concurrently). Preexisting skin atrophy (may be exacerbated due to atrophigenic properties of corticosteroids).
