ZERBAXA is contraindicated in patients with: Hypersensitivity to the active substances or to any of the inactive excipients; Hypersensitivity to any cephalosporin antibacterial agent; Severe hypersensitivity (e.g., anaphylactic reaction, severe skin reaction) to any other type of beta-lactam antibacterial agent (e.g., penicillins or carbapenems).