Vfend Indications/Uses

Voriconazole is a broad spectrum, triazole antifungal agent and is indicated in adults and children aged 2 years and above as follows: Treatment of invasive aspergillosis; Treatment of fluconazole-resistant serious invasive Candida infections (including C. krusei); Treatment of serious Candida infections including esophageal candidiasis; Treatment of candidemia in non-neutropenic patients and the following Candida infections: disseminated infection in skin and infections in abdomen, kidney, bladder wall and wounds; Treatment of serious fungal infections caused by Scedosporium spp. and Fusarium spp.; Prevention of breakthrough of fungal infections in febrile high-risk neutropenic patients.
Prophylaxis in patients ≥12 years old who are at high risk of developing invasive fungal infections. The indication is based on a study which includes patients ≥12 years old undergoing haematopoietic stem cell transplantation.
Voriconazole should be administered primarily to immunocompromised patients with progressive, possibly life-threatening infections.