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Pregnancy: Beta-blockers reduce placental perfusion, which may result in intrauterine fetal death, and immature and premature deliveries. In addition, adverse effects (especially hypoglycemia and bradycardia) may occur in the fetus and neonate. There may be an increased risk of cardiac and pulmonary complications in the neonate in the postnatal period. There is no evidence from animal studies that Vacodil has any teratogenic effects.
There is no adequate clinical experience with Vacodil in pregnanct women.
Vacodil should be used during pregnancy unless the potential benefit outweighs the potential risk.
Lactation: Animal studies demonstrated that Vacodil or its metabolites are excreted in breast milk. It is not known whether Vacodil is excreted in human milk. Breast-feeding is therefore not recommended during administration of Vacodil.
