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Pregnancy: Twinrix should be used during pregnancy only when clearly needed and when the possible advantages outweigh the possible risks for the foetus.
The effect of Twinrix on embryo-foetal, peri-natal and post-natal survival and development has not been prospectively evaluated in clinical trials.
The effect of Twinrix on embryo-foetal, peri-natal and post-natal survival and development has been assessed in rats. Such animal studies do not indicate direct or indirect harmful effects with respect to fertility, pregnancy, embryonal/foetal development, parturition or post-natal development.
Lactation: Adequate human data on use during lactation and adequate animal reproduction studies are not available. Twinrix should therefore be used with caution in breastfeeding women.
