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Incompatibilities: The injectable solution must not be mixed with other products.
If desired, Fentanyl may be mixed with 0.9 % sodium chloride and 5 % glucose solutions.
Such dilutions are compatible with plastic infusion sets. These should be used within 24 hours of preparation.
Fentanyl citrate is reportedly physically incompatible with pentobarbital sodium, methohexital sodium, thiopental sodium and nafcilline.
Special Precautions for Disposal and Other Handling: The injection is for single patient use and should be used immediately after opening. The injection should not be used if particles are present. Any unused portion should be discarded.
The product can be used either undiluted or diluted. Dilution ranges tested with 0.9 % sodium chloride and 5 % glucose solutions are 1:1 and 1:25. Hence the maximal dilution must not exceed 1 part fentanyl with 25 parts 0.9 % sodium chloride and 5 % glucose solutions.
