Stacytine Adverse Reactions

Immune system disorders: Uncommon: Hypersensitivity. Very rare: Anaphylactic shock, anaphylactic/anaphylactoid reactions.
Nervous system disorders: Uncommon: Headache.
Ear and labyrinth disorders: Uncommon: Tinnitus.
Cardiac disorders: Uncommon: Tachycardia.
Vascular disorders: Very rare: Haemorrhages.
Respiratory, thoracic and mediastinal disorders: Rare: Bronchospasm, dyspnoea.
Gastrointestinal disorders: Uncommon: Stomatitis, abdominal pain, nausea, vomiting, diarrhea. Rare: Dyspepsia.
Diseases of skin and subcutaneous tissue: Uncommon: Urticaria, rash, angioedema, pruritus, Exanthema.
General disorders and administration site conditions: Uncommon: Fever. Not known: Oedema of the face.
Investigations: Uncommon: Low blood pressure.
The occurrence of serious skin reactions such as Stevens-Johnson syndrome and toxic epidermal necrolysis have been reported in temporal association with the use of acetylcysteine. In most of these cases reported at least one other drug was administered at the same time, which may have possibly enhanced the described mucocutaneous effects.
In case of recurrence skin and mucosal lesions, medical advice should be sought at once and the use of acetylcysteine terminated immediately.
A decrease in platelet aggregation in the presence of acetylcysteine has been confirmed in various studies. The clinical significance of this has not been determined.
Acetylcysteine may have an undesirable effect on the gastric mucosa in patients with a history of peptic ulcer or peptic ulcer.