Hydrocortisone penetrates the placenta. There is however no reason to abstain from clearly indicated therapy. A newborn of a mother who has received pharmacologic doses of hydrocortisone during pregnancy should be monitored for potential hypoadrenalism. Hydrocortisone is excreted in breast milk. Breast feeding is possible during pharmacological low dose therapy. When doses exceed 100 mg/day, nursing should be avoided for a few hours after drug administration.
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