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Renson

Renson

hydrocortisone

Manufacturer:

Renata Limited

Distributor:

Medispec
Concise Prescribing Info
Contents
Hydrocortisone
Indications/Uses
Adrenocortical insufficiency (Addison's disease), hypopituitarism, congenital adrenal hyperplasia. Conditions where systemic glucocorticoid therapy is indicated.
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Dosage/Direction for Use
Adult Replacement therapy 20-30 mg daily. Other indications 40-200 mg daily. Higher doses: In short-term use for special indications. Childn Adrenocortical insufficiency 7.5-15 mg/m2 daily in 3 equal doses. Congenital adrenal hyperplasia 10 mg/m2 daily in 3 divided doses. Hypopituitarism 2.5 mg tds.
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Overdosage
View Renson overdosage for action to be taken in the event of an overdose.
Administration
May be taken with or without food.
Contraindications
Hypersensitivity. TB, other acute or chronic bacterial & viral infections w/o antibiotic or chemotherapeutic protection.
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Special Precautions
Stress situations eg, injuries, trauma, infections or surgery; acute psychosis, peptic ulcer, diabetes, osteoporosis, glaucoma, HTN; pheochromocytoma crisis. Avoid abrupt w/drawal. Concomitant use w/ live virus vaccines. Long-term systemic glucocorticoid therapy. May affect ability to drive & use machines. Pregnancy & lactation.
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Adverse Reactions
Mineralocorticoid effect; adrenocortical insufficiency; hypotension, hypoglycemia; glucocorticoid w/drawal syndrome.
Drug Interactions
Increased clearance & reduced t½ w/ phenytoin, phenobarb, carbamazepine, rifampicin, antithyroid drugs. Weakened effects of anticoagulants, antidiabetics. Muscle weakness w/ anticholinesterase. Increased risk of hypokalemia w/ diuretics, amphotericin B. Increased risk of anti-inflammatory analgesic-induced peptic ulcer. Increased risk of systemic side effects w/ CYP3A inhibitors eg, cobicistat-containing products.
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Storage
View Renson storage conditions for details to ensure optimal shelf-life.
Description
View Renson description for details of the chemical structure and excipients (inactive components).
Action
View Renson mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class
Corticosteroid Hormones
ATC Classification
H02AB09 - hydrocortisone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Presentation/Packing
Form
Renson tab 10 mg
Packing/Price
3 × 10's
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