Sign Out
On no account should PLAZILIN injectable be diluted for injection as this will upset the isotonicity and stability of the drug IV injection of metoclopramide should be given slowly over 1 to 2 minutes because rapid administration may cause intense feeling of anxiety and restlessness followed by drowsiness. The recommended dosage of metoclopramide need not be exceeded, as increasing the dose does not produce a corresponding increase in clinical response.
WARNING: Avoid doses exceeding 0.5mg/kg/day.
Extrapyramidal effects, especially dystonic reaction of metoclopramide are more likely to occur in children shortly after initiation of therapy, and usually with doses higher than 0.5mg per kg of body weight per day.
