Plazilin Dosage/Direction for Use

DOSAGE: Total daily dose of metoclopramide, especially for children and young adults, should not normally exceed 0.5mg/kg body weight.
Nausea and Vomiting: Metoclopramide injection is effective in relieving nausea and vomiting induced by: Gastroduodenal disorders like flatulent dyspepsia, gastritis, gastroenteritis, duodenal ulser and hiatus hernia;
Hepato-biliary disorders, uremia, cardiac disease, radiation therapy and migraine;
Drug like digitalis, metronidazole, pethidine morphine, include cancer chemotherapy etc.
Adults: IM: 2ml (10mg) of PLAZILIN injection 1 to 3 times daily.
IV: 1 ampoule i.e. 2ml (10mg) of PLAZILIN injection as and when required.
Children: 0.5 mg/kg body weight per day, in 3 to 4 divided doses.
Gastro-Intestinal Disorders: Delayed gastric emptying, gastric stasis and gastro-esophageal reflux (GER) Metoclopramide injection is useful for the relief of symptoms associated with delayed gastric emptying or with acute and recurrent gastric statis. Symptom of delayed gastric emptying such as anorexia, nausea, vomiting, flatulence, pain in abdomen after meals, early satiety and heartburn respond well to metoclopramide injection.
Anaesthesia in surgery / gynaecology-obstetrics: For control of pre/post-operative nausea, vomiting, injection Metoclopramide 1 ampoule (10mg) I.M.
For control of analgesic-induced vomiting, Injection Metoclopramide 1 ampoule (10mg I.M. at a different site, simultaneously with parenteral analgesic (eg, Pethedine, morphine, etc).
Prior to induction of anaesthesia in case of emergency surgery or obstetric manoeuvers in patients with full stomach to prevent vomiting and aspiration of vomitus (mendelsons syndrome). Metoclopramide Injection 1 ampoule (10mg) I.M. or I.V. preferably 1 to 1 1/2 hour before induction of anaesthesia.
Radiology: Metoclopramide Injection by hastening gastric emptying shortens the duration of barium meal examination of upper gastrointestinal tract in radiology. Metoclopramide improves the clarity of sharpness of the X-ray film by eliminating gas shadow.
Parenteral: 1 to 2 ampoules (10 to 20 mg) of metoclopramide injection I.M. 10 to 15 minutes or I.V. 5 to 10 minutes before the barium meal.
Diagnostic procedure in gastroenterology: Metoclopramide Injection is useful in: Facilitating the passage of a tube in the duodenum and Rapid and convenient endoscopy. Metoclopramide Injection, 1 to 2 ampoules (10 to 20mg) I.M. is given 10-15 minutes before the procedure.
Mode of administration: Slow Intravenous or Intramuscular route.