It has been reported that the hepatic enzyme cytochromes P450 2C19 (CYP2C19) and 3A4 (CYP3A4) are involved in the metabolism of PARIET. [See Pharmacology: Pharmacokinetics under Actions.]
Precautions for coadministration: PARIET should be administered with care when coadministered with the following drugs. (See Table 10.)
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