Each light yellow, film-coated tablet (enteric coated tablet) contains 10 mg or 20 mg of rabeprazole sodium. (See Table 1.)
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Physicochemistry: Nonproprietary name: Sodium Rabeprazole(JAN).
Chemical name: (±)-sodium2-[[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methylsulfinyl]-1H-benzimidazole.
Molecular formula: C18H20N3O3SNa.
Molecular weight: 381.43.
Sodium rabeprazole occurs as a white to pale yellowish white powder. It is odorless. It is very soluble in water and in methanol, freely soluble in dehydrated ethanol and in ethyl acetate, and practically insoluble in ether and in hexane.
It shows no optical rotation.
It is hygroscopic.
Melting point: 225°C (with decomposition).
Partition coefficient: about 214 (pH7.0, water:octanol).