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Each pre-filled syringe contains 0.25 mg of ganirelix (INN) in 0.5 ml aqueous solution. The active substance ganirelix is a synthetic decapeptide with high antagonistic activity to the naturally occurring gonadotrophin releasing hormone (GnRH). The amino acids at positions 1, 2, 3, 6, 8 and 10 of the natural GnRH decapeptide have been substituted resulting in N-Ac-D-Nal(2)1, D-pClPhe2, D-Pal(3)3, D-hArg(Et2)6, L-hArg(Et2)8, D-Ala10]-GnRH with a molecular weight of 1570.4.
Excipients/Inactive Ingredients: Acetic acid, Mannitol, Water for injections.
The pH may have been adjusted with sodium hydroxide and acetic acid.
