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The following side effects can occur: Headache, a sensation of warmth or flushing, hiccups and occasional, asymptomatic increases in liver function tests have been reported. Ondansetron is known to increase large bowel transit time and may cause constipation in some patients.
There have been rare reports of immediate hypersensitivity reactions sometimes severe including anaphylaxis.
There have been rare reports suggestive of extrapyramidal reactions eg, oculogyric crisis/dystonic reactions without definitive evidence of persistent clinical sequelae.
Seizures have been rarely observed. There have been rare reports of chest pain with or without ST segment depression, arrhythmias, hypotension and bradycardia.
