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Side effects of paracetamol rare and usually mild, although haematological reactions have been reported. Skin rashes and other hypersensitivity reactions occur occasionally.
Paracetamol may cause cutaneous hypersensitivity reactions including skin rashes, angioedema, Stevens Johnson Syndrome / Toxic Epidermal Necrolysis have been reported.
Side effects of orphenadrine citrate include dryness of mouth, tachycardia, palpitation, urinary hesitancy or retention, blurred vision, dilation of the pupils, increased ocular tension, weakness, nausea, headache, dizziness, constipation and drowsiness. These effects can usually be eliminated by reducing the dose.
Sedation, skin rashes and other allergic reactions are very uncommon adverse effects. Infrequently an elderly patient may experience some degree of mental confusion. Very rare cases of aplastic anaemia associated with the use of orphenadrine have been reported.
