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Pregnancy: NICARDIA-XL-30 should not be used during pregnancy unless the clinical condition of the woman requires treatment with nifedipine. NICARDIA-XL-30 should be reserved for women with severe hypertension who are unresponsive to standard therapy.
Careful monitoring of blood pressure must be exercised when administering NICARDIA-XL- 30 with I.V. magnesium sulfate, owing to the possibility of an excessive fall in blood pressure, which could harm both mother and foetus.
Lactation: NICARDIA-XL-30 is excreted in the breast milk. The NICARDIA-XL-30 concentration in the milk is almost comparable with mother serum concentration. For immediate release formulations, it is proposed to delay breastfeeding or milk expression for 3 to 4 hours after drug administration to decrease the NICARDIA-XL-30 exposure to the infant.
