Vitamin D: Adverse effects are similar to those encountered with excessive vitamin D intake. The early and late signs and symptoms of Vitamin D intoxication associated with hypercalcaemia include: Early: weakness, headache, somnolence, nausea, vomiting, dry mouth, constipation, muscle pain, bone pain and metallic taste.
Late: Polyuria, polydipsia, anorexia, irritability, weight loss, nocturia conjunctivitis, pancreatitis, photophobia, rhinorrhea, pruritus, hyperthermia, decreased libido, albuminuria, hypercholesterolaemia, ectopic calcification, hypertension, cardiac arrhythmias and rarely overt psychosis.
Vitamin B: The vitamin B's are very well tolerated. Adverse effects are very rarely reported. However, allergic reactions to some of them have been occasionally reported.
Vitamin C: Ascorbic acid is usually well toleranted. However, allergic responses to it presenting as eczema, urticaria or asthma have been reported.
Large doses may cause diarrhoea and the formation of renal calcium oxalate calculi.
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