Moxifloxacin is an antibiotic that is used to treat community-acquired pneumonia (lung infection acquired outside of a hospital or healthcare facilities) and complicated skin infections.
This medicine may be used to treat other conditions as decided by your doctor.
Moxifloxacin injection is to be given intravenously (into the vein), infused over 60 minutes. It is delivered directly into the bloodstream via the blood vessel.
Your doctor or nurse will administer the injection for you.
The dose of Moxifloxacin will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your condition.
You must complete the entire course of this medicine. If you don't, the infection will not be properly controlled.
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Moxifloxacin.
If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
Do not use this medicine if you ever had an allergic reaction (rashes, breathlessness, swollen eyes) to Moxifloxacin and similar antibiotics such as ciprofloxacin, levofloxacin, lomefloxacin, nalidixic acid, norfloxacin, and ofloxacin.
Alert your doctor if you have the following conditions:
- history of tendon disorder
- abnormal heart rhythms
- electrolyte disturbances (low levels of potassium or magnesium in the blood)
- heart failure
- severe liver disease
as Moxifloxacin may not be suitable for you.
Inform your doctor if you have the following conditions:
- fits or seizures
- heart disease
- G6PD (abnormal activity of the red blood cell/ an inherited blood disorder that affects the red blood cell)
- diabetes
- mental illness or history of mental illness
- rheumatoid arthritis (an autoimmune disease that affects the joints)
- kidney disease
- liver disease
- myasthenia gravis (muscle weakness disorder)
Let your doctor know if you are pregnant or breastfeeding.
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
- Your doctor may need to perform routine blood tests to make sure that your heart, liver, and kidney function is normal before you take this medicine and thereafter depending on your doctor’s advice.
- Your doctor may also need to monitor your blood sugar level closely.
- For as long as you are taking this medicine, you may need to have your eyes checked regularly. Your doctor will advise you about how often you need to have these tests.
Moxifloxacin may cause dizziness or transient loss of vision. If affected, do not drive or take part in any activity in which you need to be alert or need to see clearly.
Other side effects include any of the following: vomiting, rash, muscle and joint pain, anaemia, eye irritation, infections.
Moxifloxacin may also cause your skin to be more sensitive to sunlight. Avoid direct or prolonged exposure to the sun or ultraviolet (UV) light, including tanning beds and sun lamps.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- rashes, breathlessness, swollen face or throat
- rashes with peeling of the skin or blistering of the lips, mouth or eyes accompanied by fever
- pain, tenderness, and mild swelling in limbs or joints
- ruptured tendon usually characterized by a snap or pop you hear or feel, severe pain, bruising, and marked weakness on the affected area e.g. kneecap, shoulders, heel
- numbness or tingling sensation in the hands and feet
- irregular heartbeat
- unusual changes in mood or behaviour (being too depressed, agitated, having thoughts of self-harm, seeing, hearing or feeling things that are not existent)
- seizures
- symptoms of hypoglycemia or low blood sugar e.g. dizziness, tremor, shaky hands, feeling hungry, weak or confused, problems speaking
- stomach pain, yellowing of the skin or eyes, dark urine, pale stools
- severe diarrhoea
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking any of these medicines:
- medicines for heart disease e.g. quinidine, amiodarone, disopyramide, sotalol
- medicine for cold or allergy e.g. terfenadine, loratadine, astemizole, mizolastine
- medicine to treat depression e.g. fluoxetine, nortriptyline
- medicine for mood disorders e.g. haloperidol
- certain antibiotics e.g. erythromycin, pentamidine
- medicine that reduce stomach acid production e.g. cisapride
- medicines for HIV infection e.g. saquinavir
- medicine for diabetes e.g. glibenclamide, insulin
This list does not include all medicines that may interact with Moxifloxacin.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Avoid alcohol.
Store below 25°C.
Once opened, use the ampoules immediately. Throw away any solution that is not used.
If you notice that the injection has changed colour or has become cloudy, do not use it. Throw it away and use a new injection.
Medicines must not be used past the expiry date.
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