Discontinue use if severe hypersensitivity, signs & symptoms suggestive of severe cutaneous ARs, antibiotic-associated diarrhoea & colitis or 1st sign of tendinitis occur. Not recommended in patients w/ complicated pelvic inflammatory disease; MRSA infections. Avoid use in patients w/ known history of serious ARs w/ quinolone- or fluoroquinolone-containing products; myasthenia gravis. Increased risk of aortic aneursym & dissection. Patients w/ ongoing proarrhythmic conditions eg, acute myocardial ischaemia or QT prolongation; bullous skin reactions eg, SJS, TEN; CNS disorders, risk factors predisposing to seizures or lowering seizure threshold; sensory or sensorimotor polyneuropathy; psychosis or history of psychiatric disease; solid organ transplants; vision disorders; G6PD deficiency. Monitor blood glucose in diabetic patients. Maintain adequate fluid intake. Avoid exposure to UV irradiation, extensive or strong sunlight. Interference w/
Mycobacterium spp culture test. Not to be taken by patients w/ galactose intolerance, total lactase deficiency or glucose-galactose malabsorption. Avoid concomitant use w/ corticosteroids. Concomitant use w/ medications reducing K levels. May affect ability to drive or use machines. Severe hepatic disorders. Renal impairment. Not to be used during pregnancy. Childn & adolescents <6 yr. Elderly >60 yr.
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