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General contraindications related to regional anesthesia should be taken into account with the use of any regional anesthetic agent, including levobupivacaine. Levobupivacaine solutions are contraindicated in those with a known sensitivity to local anesthetic amide agents.
Levobupivacaine is contraindicated in patients with severe hypotension such as cardiogenic or hypovolemic shock (see Precautions).
Levobupivacaine is contraindicated for use in paracervical block in obstetrics, and for intravenous regional anesthesia (e.g., Bier's block).
Additionally, levobupivacaine 7.5 mg/ml solution should not be employed for any obstetric procedures due to an enhanced risk for cardiotoxic events based on experience with bupivacaine.
